The West-end of Main Street houses the newer businesses.

Stater Brother's Center with Blockbuster Video, Rite-Aid, Ramona's Florist, Manzanita Press, Marketing Worx, Quiznos, Rubio's Fish Tacos and more.

Albertson's Center offers Sav-On Drugs, Water Depot, Hair Styling Shop, Donut Shop, Hallmark Shop, Nuevo Grill & Cantina, Bank of America, and more.

Kmart Center offers Radio Shack, Donut Shop, Hair Styling Shop, Subway, Taco Bell, Big O Tire of Ramona and Oil Changers.

Sun Valley Center is home of some of Ramona's oldest and most respected businesses. Orchards Marketplace, opened in 2001. Included in the mall is a pawn shop, stove shop,P&M Computers and liquor store with gas station and more.